An 88 year old female with chest and severe upper abdominal tenderness for investigation with a past history of IHD and hypertension, was referred for a Myocardial Perfusion stress test. Although SPECT Myocardial Perfusion imaging concluded that there was no myocardial ischaemia and Gated SPECT showed normal LVEF and regional wall motion, on closer observation on the cine there was a large cold area on the right side of the liver, an incidental finding in need of investigation. A CT Abdomen was recommended and performed and a large 11 X 9.8cm cyst was seen, with a number of smaller well defined lower attenuation lesions elsewhere in the liver. The possibility of malignancy was raised, but further investigations concluded smaller hepatic cysts and calcific granulomata. SPECT Myocardial cine is mainly used for motion detection and to differentiate between stomach and liver activity to assist in reporting inferior wall defects. Closer observation of cine mode playback can help in diagnosing incidental pathology such as liver disease or Sestamibi avid breast tumours in the chest.