Objective: Moyamoya disease is a rare progressive occlusive disorder which affects the vasculature of the brain. It results in stroke like systems & can cause death due to haemorrhage. This poster follows the clinical case of a 12 year old South Korean Female diagnosed with Moyamoya disease in January 2004 & the role nuclear medicine played in her management.

Methods: The clinical history of the patient was examined closely, with all previous medical imaging reports & nursing entries collated. An extensive literature review of Moyamoya disease was then performed using a range of resources.

Results: The patient’s clinical work-up involved a range of medical imaging procedures the results of which did not provide a clear pathway for clinical management. A Nuclear Medicine Cerebral Perfusion Diamox Challenge study was subsequently performed providing a critical result. The results of this study were indicative of no change in vascular reserve both pre & post Diamox infusion. Ultimately the patient’s physicians then delayed the need for anastmosis surgery, with alternate methods of treatment required.

Conclusion: Overall this case highlights the need for functional imaging & the importance of drug therapies including Diamox in nuclear medicine procedures. This study ensured the patients quality of life was maintained & eliminated any risk involved in performing further surgery.